Pulling an all-nighter is a temporary antidepressant : Short Wave

https://www.npr.org/2023/11/03/ [login to see] /no-sleep-depression-mice-dopamine-antidepressant
What your parents didn't tell you about pulling an all-nighter? It might just ease depression for several days. At least, that's what researchers found happened to mice in a study published in the journal Neuron Thursday.

Most people who've stayed up all night know the "tired and wired" feeling they get the next day. The body might be exhausted, but the brain feels jittery, hyperactive or even giddy. Even after these changes wear off, sleep loss can have a strong antidepressant effect in people that lasts several days.

But researchers hadn't figured out why sleeplessness might have this effect —until this study from neurobiologists at Northwestern University.