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SSG Michael Noll
5
5
0
Hope this means they can make some headway and maybe cure something sister Charlie!?!
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Lt Col Charlie Brown
Lt Col Charlie Brown
2 y
Protein misfolding is linked to a number of diseases so once someone is identified as having that issue, the option to intervene pharmacologically is possible.
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Lt Col Charlie Brown
Lt Col Charlie Brown
2 y
Protein misfolding and aggregation is the common cause and pathological mechanism of neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS), PD, and Huntington’s disease (HD). Autophagy can selectively remove abnormally folded proteins via the lysosomal pathway. Thus, pharmacological manipulation of autophagy may have neuroprotective effects in certain neurodegenerative diseases.
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SSG Michael Noll
SSG Michael Noll
2 y
Sister Charlie, some help for neurodegenerative diseases, thanks for the explanations.
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SFC Ralph E Kelley
1
1
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Hmmm... Proof?
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