Ptolemaic dynasty - Wikipedia

On August 12, 30 BC, Cleopatra VII Philopator, the last ruler of the Egyptian Ptolemaic dynasty, commited suicide allegedly by inducing an asp (Egyptian cobra) to bite her. From the article:

"Ptolemy, one of the seven somatophylakes (bodyguards) who served as Alexander the Great's generals and deputies, was appointed satrap of Egypt after Alexander's death in 323 BC. In 305 BC, he declared himself Ptolemy I, later known as Sōter "Saviour".

The Egyptians soon accepted the Ptolemies as the successors to the pharaohs of independent Egypt. Ptolemy's family ruled Egypt until the Roman conquest of 30 BC.

All the male rulers of the dynasty took the name Ptolemy. Ptolemaic queens regnant, some of whom were the sisters of their husbands, were usually called Cleopatra, Arsinoe or Berenice. The most famous member of the line was the last queen, Cleopatra VII, known for her role in the Roman political battles between Julius Caesar and Pompey, and later between Octavian and Mark Antony. Her apparent suicide at the conquest by Rome marked the end of Ptolemaic rule in Egypt."