Posted on Nov 13, 2015
CPO Andy Carrillo, MS
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"I'm excited to report that MAPS just received final approval from our Institutional Review Board (IRB) to move forward with our new US MDMA/PTSD study. Michael Mithoefer, M.D. and Annie Mithoefer, BSN will conduct this new study in Charleston, South Carolina. Together they ran the previous MAPS-sponsored US MDMA/PTSD study, which successfully demonstrated both safety and efficacy in treating treatment-resistant PTSD patients with MDMA-assisted psychotherapy. This new study will be conducted entirely with U.S. veterans of war with PTSD, mostly from Iraq and Afghanistan, with a few from Vietnam. Unlike the Mithoefers first study, which only had two groups (inactive placebo and full-dose MDMA), this study will compare three doses of MDMA--30 mg, 75 mg, and 125 mg, in an effort to enhance the double-blind. Most importantly, we will be testing what may become the protocol design that will be used in our large-scale, multi-site Phase 3 studies."

Research to the rescue. High-tech brain scans reveal that psilocybin inhibits blood flow in parts of the brain that regulate sensory input. Less blood flow means less regulation. Flooded with perceptions, a psilocybinized brain can help PTSD patients reprogram their fears, Doblin says. New tools also provide new insight into LSD's ego-dissolving "catharsis effect." And the ecstasy chemistry: MDMA reduces blood flow in the fear-processing amygdala while increasing blood flow in the prefrontal cortex, which facilitates our ability to put things into context.

"With MDMA, the fear circuitry is reduced," Doblin explains. This helps PTSD patients remember and re-examine long-buried aspects of their traumas. Aided by MDMA, "these memories don't immediately go straight to fear." Say you were traumatized by a bat-wielding, red-hatted assailant. Under MDMA, "the neural pathways connecting bats, red hats and fear are not so strong." Recontextualized in an MDMA-activated prefrontal cortex, triggers lose their power—sometimes forever, he says.

"Under the influence of MDMA, people can make emotional changes that persist after the MDMA is out of their systems." On MDMA, "you operate on this much smoother level, and then you lose it—but not all of it. You get so much material from that experience, which you can learn to integrate."
https://www.thefix.com/content/prescription-lsd?page=all

http://www.maps.org/maps-media/update
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Responses: 4
CSM Michael J. Uhlig
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I went through the unit prevention leader course at Fort Hood (where they wrote the regulation AR 600-85) and part of the course was we had to research an assigned drug and present a briefing to the rest of the class.....the subject drug I had was MDMA (Ecstacy) so I went through the FBI website to get my sources and pissed off the instructor with my briefing.....more people died per 1,000 fishing on a boat than died using the drug MDMA......so my thesis was it was safer to use that drug than to go fishing....I did not make a friend with the instructor!
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CMSgt James Nolan
CMSgt James Nolan
9 y
Logical conclusion.  I can see the instructor now.....
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CPO Andy Carrillo, MS
CPO Andy Carrillo, MS
9 y
CMSgt James Nolan - You probably compounded his PTSD and he is now shifting his feet at the head of the line in SC. Check out the interesting history of MDMA and the Catholic priest who became a millionaire selling it:
http://www.colorsmagazine.com/stories/magazine/83/story/take-your-love-to-a-higher-level
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CSM Charles Hayden
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During one of my surgeries, the anesthesia Ketamine was used. When I later commented about the wild scenes I visualized while under it's affects, the MD told me what had been used and that it was next door to LSD?
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MSG Unit Supply Specialist
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Of couse they did...it keeps big pharma booming over growing a natural weed in one's backyard...
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