Israeli aircraft struck Syrian military targets on Monday, the Israeli army confirmed in a rare statement.
Syrian state media acknowledged the strikes, reporting unspecified "material damage" at military outposts near the capital Damascus.
The Israel Defense Forces (IDF) said it was retaliation for a bombing attempt.
The IDF said earlier it had killed four men planting explosives near the Israeli-occupied sector of Golan Heights late on Sunday.
Surveillance footage showed the group engulfed in an explosion.
Military spokesman Lieutenant-Colonel Jonathan Conricus said it was too soon to say if the men belonged to a specific organisation, but that Israel held "the Syrian regime accountable".