Looking for a new rifle, what do you suggest?

I would get something in .270 win or 30-06 class, ammo is cheaper than most. Both are well priced in Remington, Savage, Winchester, etc.

I shoot Savage .270win with Nikon optics , and Savage .308 win with Vortex both sighted in at 100yds with sub-MOA. This year I shot my elk with the .270, dropped him on the spot at a 100 yds. Furthest shot was a buck at 350 yds and dropped him on the spot.

Are you looking for hunting, recreational, or sports shooting?

I'll second SPC Fewell's recommendation of the the Ruger Gunsite Scout. I picked up a .308/16inbarrel last year and have really enjoyed it.
However... does the $1k include your optics or just the rifle? That may alter a few recommendations made by others.

I have a Remington 300 ultra mag. Model 700. A very sweet powerful high power rifle. Will drop any big game in north America. You might be able to get into that rifle used for around a $1000. But if it don't have a scope on it then you have to worry about that. I would never go with any other rifle. Just my opinion boss. Here is a picture of mine.

Look at the Thompson Center Diminsion. Has 4 interchangeable bolts/magazine groups, and covers a total of 10 calibers. Shot SUB MOA right out of the box for me. had a less then 1 inch shot group at 300 yrds with 10mph crosswind.... covered all 3 shots with a dime at 100yrds. All calibers in each "category" use the same bolt/mag. A group is like the 223, etc, B group is stuff like 308, 7mm-08, C Group is like the 30-06 (if I remember right), and group D is 7mm Rem Mag and .300 Rem Mag. LOVE IT. Price is pretty good also for such a great shooter!

A Remington .308 semi Auto is an awesome rifle.

It depends on what kind of game you plan to hunt. I've hunted primarily western big game with a 300 Win Mag (Alaskan brown bear, Mt Goat, Dall Sheep, as well as black tail deer). I went with a stainless and synthetic stalk, which is lightweight and good for any climate. Mine (Browning) went for about $800.

I will admit I am no expert on rifles, but it appears you have a pretty good selection. How about something like a .50 muzzleloader?

For home defense, I have a New England, pardner 12 gauge loaded with #4 turkey loads so it will kill who I am aiming at and won't go through the walls into the neighbors house.
For the area I live and hunt, I use a Remington 870 in the 12 gauge model, I hunt deer, ducks, geese, grouse, and have taken it bear hunting.

I mean what do you want it for? Hunting big game, varmints, Hadji??